WarrZuckerman586

Signs of serotonin syndrome'

Irritability, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Chill, Tremor, Cerebral status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Shaking, Pain in the stomach, Diarrhea, Perspiration, Increased heat, Hypertension. All these tend to be signs or symptoms of serotonin syndrome. All can look normally within the first 24 hours soon after taking a great o.d. of serotonin drugs. This signs are on cognitive degree, autonomic level and SoNS level. Serotonin Toxidrome come often right after o.d. of serotonin drugs as well as drug combination that increase synaptic serotonin. Drugs that tend to be understand to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Crack, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Li, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Pep pill. Because serotonin toxidrome it's definitely not tested in the laboratory for diagnosis, signs tend to be the one need seen. The best set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are as follows: discontinuing drugs that made the overdose posible as well as drugs which can contribute management of serotonin antagonist (eg. cyproheptadine) for sever cases of toxicity for agitation, muscular tissue stiffness and also capture like movements, benzodiazepines (Valium, Ativan) Intra venous fluids Because serotonin syndrome is not easy to diagnose, prevention is needed for any serotonin drugs mixture of which may lead to 5-hydroxytryptamine toxicity.

''Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642 Prator BC. Serotonin Syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5. Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.''